دانلود مقاله انگلیسی با ترجمه آزمایش براساس ترانسکریپتوم آلرژی زاهای گردۀ برنج
عنوان فایل ترجمه فارسی: آزمایش مبنی بر ترانسکریپتوم آلرژی زاهای گردۀ برنج.
عنوان نسخه انگلیسی: Transcriptome-Based Examination of Putative Pollen Allergens of Rice
مرتبط با رشته : زیست شناسی
تعداد صفحات مقاله فارسی: ۱۷ صفحه
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قسمتی از متن انگلیسی:
Ory s 12 is the pollen allergen corresponding to pollenexpressed profilin, which has long been known as a potent allergen (Valenta et al., 1991). Since the known functional role of profilin—principally as a protein involved with controlling actin polymerization—is exclusively intracellular, the release of profilin from pollen as an allergen is likely the result of protein released from damaged, non-intact or dead pollen, possibly forming small aerosol particles that may be inhaled (Swoboda et al., 2004). In rice, pollen-related profilin A transcripts appear to be highly expressed (intensity 8.120 log2) and up-regulated by 11.74 log2 times (.20003) above seedlings, according to microarray results. MPSS indicates that transcript abundance is among the top 30 signatures, of which two loci were specific for pollen-expressed profilin; there was strong proteome support (supplementary data). In rice, the two loci active exclusively in pollen are LOC_Os10g17660 and LOC_Os10g17680. These are inverted on opposite strands and share high sequence similarity, differing by only six nucleotides. In the rice genome, there are only three loci devoted to profilin, of which two seem only to be expressed in pollen (see supplementary data). All other sporophytic expression seems to correspond to a remaining profilin-2 (LOC_Os06g05880). Profilins are typically involved in the sequestration of actin monomers and are highly expressed in pollen, presumably as a protein that modulates polymerization and the dynamic nature of the elaborate actin cytoskeleton of elongating pollen tubes. These appear to be strong candidates.
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