دانلود ترجمه مقاله استفاده از سایتوکین به عنوان یک بزاق در غربالکری اسکواموس سل کارسینوما دهان
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The use of saliva for diagnosis of disease has been sought centuries ago. However, the introduction of molecular laboratory techniques in 1980s has drawn more attention to saliva as a tool for detection of disease and for health monitoring in general.[23] Oral fluid analysis has been proved useful for detection of Sjögren’s syndrome,[24,25] diabetes mellitus,[26] infection with Helicobacter pylori, [27] Cushing syndrome,[28] HIV,[29-31] and hepatitis C virus.[32,33] It is now being routinely used for the detection of abused as well as therapeutic drugs.[20] Saliva has also been suggested for breast cancer screening programs by detecting Her2\neu.[34-36] Withal, diseases of the oral cavity have been the most attractive ones for saliva diagnostics researchers, and the use of saliva for detection of dental caries[37] and periodontal diseases[38,39] has been suggested. Salivary diagnostics for OSCC, if becoming a routine, would also comprise a suitable tool for population screening, monitoring of patients at risk of recurrent tumor, and consequently for improving the survival rate of patients with this disease.[23,40]
